![]() ![]() It was associated with approximately twice the 10-year total mortality, cardiovascular mortality and major coronary event rate compared with the overall rate in each Framingham category. įramingham risk score have no relation with CAE, it only predicts severity of CAD, the hazard ratios remained elevated on adjusting for Framingham Risk Score, 2.9 (2.3 to 3.7) for men and 3.0 (2.0 to 4.4) for women. Previous studies founded non-significant correlation between CAE group and control group as regarding criteria of metabolic syndrome risk score DM, HTN, TG and HDL. ![]() Framingham Risk Scoring System (FRS) and metabolic syndrome risk score are also a simple and feasible methods that can be used for prediction of obstructive coronary artery disease in patients with coronary artery ectasia and also in the detection of its severity. We hypothesize that the cardiac events outcomes in patients with coronary artery ectasia could be predicted. īecause CAE renders patients to higher risk of myocardial ischemia irrespective of the extent of stenosis, more studies characterizing this understudied disease entity are necessary to further improve management. Of the acquired cases, 50% are attributed to atherosclerosis while 10% to 20% are associated with inflammatory and connective tissue diseases (like Ehlers-Danlos syndrome, Kawasaki disease and scleroderma), syphilis, and bacterial infections. Twenty to 30% of cases of coronary ectasia are considered congenital and the others are acquired. The incidence of coronary artery ectasia has been reported to be 0.3 to 5.3% of patients undergoing coronary angiography. Keywords: Coronary artery ectasia FRS MSS TIMI flowĬoronary Artery Ectasia (CAE) is the abnormal dilatation of a segment of coronary artery to 1.5 times or more the size of adjacent normal segment of the artery. However, FRS and M$S had no significant correlation to it (P 0.6)Ĭonclusion: TIMI flow was the main significant predictor of cardiovascular events in patients with coronary artery ectasia however, FRS and M$S had no role in prediction or risk stratification in CAE patients. TIMI flow was the main significant variable when correlating to the incidence of cardiovascular events (P <0.001). However, in correlating between these different scores and the different ectatic segments in number and sizes only TIMI flow had the significant correlation (P <0.001). However, none of them showed any significant difference between the 2 groups. Results: We used M$S and FRS to stratify the risk of all the patients. All patients were subjected to detailed history, physical examination, laboratory investigations, electrocardiography, conventional echocardiography, diagnostic coronary angiography and follow up by metabolic, Framingham risk scores and TIMI flow. Methods: The study was conducted on 187 patients, 36 patients with angiographic evidence of isolated coronary artery ectasia and 151 controls. Objective: to determine the risk factors and predictors of adverse cardiovascular events in patients with coronary artery ectasia without obstructive CAD using metabolic syndrome risk score and Framingham risk score. Background: Coronary artery ectasia is abnormal dilatation of a segment of coronary artery to 1.5 times or more the size of adjacent normal segment, in patients with CAE the adverse outcomes could be anticipated from their risk profiles using risk scoring systems like metabolic and Framingham risk scoring systems. ![]()
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